Module Details

Module Code: ZSCI H4101
Module Title: Molecular Genetics and Immunology 2
Title: Molecular Genetics and Immunology 2
Module Level:: 8
Credits:: 5
Module Coordinator: Paula Rankin
Module Author:: Ann-Marie Enright
Domains:  
Module Description: The aim of this module is to give students a functional competency in the theoretical knowledge and the methods of molecular genetics, biotechnology and immunology.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Discuss the mammalian immune response with respect to antibody production and vaccine efficacy.
LO2 Explain the basis of antibody and antigen reactions and demonstrate how this interaction can be commercially exploited.
LO3 Evaluate the production of monoclonal and polyclonal antibodies, their current and potential commercial roles and their industrial, environmental and therapeutic application.
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is recommended before enrolment in this module.
No recommendations listed
Co-requisite Modules
No Co-requisite modules listed
Additional Requisite Information
No Co Requisites listed
 
Indicative Content
Immunology
Mammalian immune response: Overview of the mammalian immune response with respect to antibody production and vaccine efficacy. Antigens and immunogens. Antibody and antigen reactions in vivo and in vitro. Antibody affinity and avidity. Structure and properties of immunoglobulins, overview of main isotypes, source of antibody diversity. Commercial antibody production: Polyclonal and monoclonal antibody production. Large-scale antibody production. Antibody purification methods. Applications of antibody and antigenic reactions, kits, monoclonal antibodies in detection, diagnostics and therapy. Vaccines: Immunization: passive and active. Vaccine production and development with respect to problems associated with human vaccines.
Practical
Practical's will be delivered as tutorials focusing on problem solving and assisting the student in the interpretation and analysis of molecular data generated through modern molecular techniques including; qPCR, Microarray analysis, Southern hybridization analysis, Eliza, Restriction digests, Primer/probe design and optimization, Manipulation of raw sequence data via bioinformatic tools, Sequencing and DNA fingerprinting. Above techniques will be adopted and substituted as appropriate. In addition to the tutorials students will be asked to review, summarise and present key research papers and current developments in topics encountered during the course of study. Material and presentations generated will be assessed on an ongoing basis.
Module Content & Assessment
Assessment Breakdown%
Practical40.00%
End of Module Formal Examination60.00%

Assessments

Full Time

No Continuous Assessment
No Project
Practical
Assessment Type Practical/Skills Evaluation % of Total Mark 40
Timing n/a Learning Outcomes 1,2,3
Non-marked No
Assessment Description
practical work sheets and paper reviews
End of Module Formal Examination
Assessment Type Formal Exam % of Total Mark 60
Timing End-of-Semester Learning Outcomes 1,2,3
Non-marked No
Assessment Description
Final examination of three hour duration
Reassessment Requirement
Exam Board
It is at the discretion of the Examination Board as to what the qualifying criteria are.

SETU Carlow Campus reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Category Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Lecture 12 Weeks per Stage 3.00 36
Laboratory Contact Practical and tutorial 12 Weeks per Stage 1.00 12
Estimated Learner Hours Non Contact Independent learning 12 Weeks per Stage 6.42 77
Total Weekly Contact Hours 4.00
 
Module Resources
Recommended Book Resources
  • J. Owen, J. Punt, S. Stranford. (2013), Kuby Immunology, 7th Edition. MacMillan Learning.
  • Peter Delves, Seamus Martin, Dennis Burton, Ivan Roitt. (2011), Roitt’s Essential Immunology, 12. Willey Blackwell.
This module does not have any article/paper resources
Other Resources
Discussion Note: