Module Details

Module Code: ZCHE C2102
Module Title: Biochemistry Metabolism
Title: Biochemistry Metabolism
Module Level:: 6
Credits:: 5
Module Coordinator: Paula Rankin
Module Author:: Aine ONeill
Domains:  
Module Description: The aim of this module is to give the student a sound knowledge of key concepts in the control of metabolism, metabolic processes and introductory enzyme kinetics as well as to develop basic laboratory technical, numerical and reporting skills with due regard to Health and Safety.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Explain how metabolism is controlled by enzymes and other mechanisms
LO2 Outline central metabolic pathways and the synthesis of ATP
LO3 Recognise the role of buffers in biochemistry
LO4 Carry out basic biochemical techniques with due regard to safety in the laboratory
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is recommended before enrolment in this module.
4504 SCIE H1111 Chemistry
Co-requisite Modules
No Co-requisite modules listed
Additional Requisite Information
No Co Requisites listed
 
Indicative Content
Buffers in biochemistry
The ionic product of water, buffers and buffering capacity, the Henderson Hasselbalch equation, the preparation of buffers, the blood buffering system
Enzymology
Classification and mode of action of enzymes. Factors influencing enzyme activity. Introduction to enzyme kinetics; Km, Vmax and Kcat, the Michaelis-Menton and Lineweaver-Burk plots
Introductory Metabolism
Definition, anabolic and catabolic metabolism. Methods of metabolic control
Metabolic Pathways
Glycolysis and gluconeogenesis. Introduction to citric acid cycle, the electron transfer chain and β-oxidation. Ketosis. Amino acid catabolism
Bioenergetics
ATP synthesis. The yield of ATP from central catabolic metabolism
Practical
The first class will cover Health &Safety regulations. Further classes will include exercises on the following or similar; the preparation and testing of bufffers, basic biochemical extraction and separation, enzymatic assays and the determination of the Km and Vmax of an enzyme. Students will also gain experience in biochemical calculations, plotting curves and laboratory report writing.
Module Content & Assessment
Assessment Breakdown%
Continuous Assessment10.00%
Practical40.00%
End of Module Formal Examination50.00%

Assessments

Full Time

Continuous Assessment
Assessment Type Examination % of Total Mark 10
Timing n/a Learning Outcomes 1,2
Non-marked No
Assessment Description
A number of short assessments
No Project
Practical
Assessment Type Practical/Skills Evaluation % of Total Mark 40
Timing Every Week Learning Outcomes 3,4
Non-marked No
Assessment Description
Practical Laboratory Book
End of Module Formal Examination
Assessment Type Formal Exam % of Total Mark 50
Timing End-of-Semester Learning Outcomes 1,2,3
Non-marked No
Assessment Description
Two hour written final examination
Reassessment Requirement
Exam Board
It is at the discretion of the Examination Board as to what the qualifying criteria are.
Reassessment Description
Re-sit examinations or repeat entire module

SETU Carlow Campus reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Category Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Lecture 12 Weeks per Stage 2.00 24
Laboratory Contact Practical class 12 Weeks per Stage 2.00 24
Estimated Learner Hours Non Contact Independent learning 15 Weeks per Stage 5.13 77
Total Weekly Contact Hours 4.00
 
Module Resources
Recommended Book Resources
  • Lubert Stryer,Jeremy Berg,John Tymoczko,Gregory Gatto. (2019), Biochemistry, WH Freeman, p.1208, [ISBN: 9781319114657].
  • David Nelson,Michael M. Cox. Principles Biochem 7e (International Ed), [ISBN: 9781319108243].
Supplementary Book Resources
  • Sareen S. Gropper,Jack L. Smith,Timothy P. Carr. (2016), Advanced Nutrition and Human Metabolism, Cengage Learning, p.640, [ISBN: 9781305627857].
This module does not have any article/paper resources
Other Resources
  • www.YouTube.
  • www.JoVE.
Discussion Note: