Module Details

Module Code: ZSCI H4102
Module Title: Pharmaceutical Science
Title: Pharmaceutical Science
Module Level:: 8
Credits:: 5
Module Coordinator: Paula Rankin
Module Author:: Brian ORourke (Science Staff)
Domains:  
Module Description: To understand the procedures in drug production from synthesis to finished product manufacture.
To develop analytical procedures for routine pharmaceutical analysis.
To understand drug registration requirements.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Understand the procedures in drug production from synthesis to finished product manufacture.
LO2 Develop analytical procedures for routine pharmaceutical analysis.
LO3 Understand drug registration requirements.Validate existing drug manufacturing plant and instrumentation.
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is recommended before enrolment in this module.
No recommendations listed
Co-requisite Modules
No Co-requisite modules listed
Additional Requisite Information
No Co Requisites listed
 
Indicative Content
Pharmaceutical preparation
1. Introduction requirements for product registration 2. Preformulation: solubility, solubilisation. Polymorphism, eutectic points, degradation profiles. 3. Formulation theory and practice: simple drug delivery vehicles. 4. Accelerated stability and shelf life. Modified release medications. 5. Nanotechnological innovation. 6. Emulsion preparation: surface tension and surface energy. Experimental techniques. 7. Surfactants, critical micelle concentration, spreading and contact angle. Lapace excess pressure. Microemulsions and liquid crystal phases. Aerosols 8. Stability evaluation and chemical assay. Product registration 9. Regulatory bodies, IMB, FDA, etc. 10. Good manufacturing processes: quality management, production activities, internal audits, calibration 11. Validation: policy, documentation, qualification of equipment and ancillaries, process and analytical validation. Cleaning validation and change control. 12. Rejection and reuse of materials. Complaints and recalls. Contract manufacture 13. Materials management. Production & in-process controls.
Module Content & Assessment
Assessment Breakdown%
Continuous Assessment10.00%
Practical20.00%
End of Module Formal Examination70.00%

Assessments

Full Time

Continuous Assessment
Assessment Type Short Answer Questions % of Total Mark 10
Timing n/a Learning Outcomes 1,2,3
Non-marked No
Assessment Description
Regular written examinations to evaluate student understanding of course content
No Project
Practical
Assessment Type Practical/Skills Evaluation % of Total Mark 20
Timing Sem 1 End Learning Outcomes 1
Non-marked No
Assessment Description
Dissolution studies of rapid release and controlled-release medications. Formulation of simple emulsion and tablets Assessment of physical stability. Assay development. 16. Use of conductivity to determine solubility products of a number of sparingly-soluble drugs. 17. Extraction by Soxhlet apparatus of podophyllin from podophyllum rhizomes.
End of Module Formal Examination
Assessment Type Formal Exam % of Total Mark 70
Timing End-of-Semester Learning Outcomes 1,2,3
Non-marked No
Assessment Description
Final year evaluation

SETU Carlow Campus reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Category Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Pharmaceutics 12 Weeks per Stage 2.00 24
Practicals Contact Laboratory practice 12 Weeks per Stage 2.50 30
Independent Learning Time Non Contact Independent Learning 15 Weeks per Stage 5.00 75
Total Weekly Contact Hours 4.50
 
Module Resources
Recommended Book Resources
  • M.E. Aulton. (2013), Pharmaceutics, 4th.
  • Loyd V. Allen Jr. PhD (Editor), Nicholas G. Popovich PhD (Editor), Howard C. Ansel PhD. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 9th.
Supplementary Book Resources
  • (2011), Goodman and Gilman's The Pharmacological Basis of Therapeutics, 12th.
  • Alison Brayfield. (2021), Martindale: The Complete Drug Reference.
  • Loyd V., Jr., Ph.D. Allen (Editor), Adeboye, Ph.D. Adejare (Editor), Shane P., Ph.D. Desselle (Editor), Linda A., Ph.D. Felton (Editor). Remington: The Science and Practice of Pharmacy, 22nd.
This module does not have any article/paper resources
This module does not have any other resources
Discussion Note: