Module Details

Module Code: ZCHE C3101
Module Title: Biochemistry 1: Metabolism
Title: Biochemistry 1
Module Level:: 7
Credits:: 5
Module Coordinator: Paula Rankin
Module Author:: Rosemary O'Hara
Domains:  
Module Description: The aim of this module is to expand the students knowledge of biochemical processes, systems and structures.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Describe the synthesis, structure, function and interactions of major biomolecules.
LO2 Describe and elucidate the major metabolic pathways; explain how metabolism is controlled and metabolic diseases occur.
LO3 Carry out a range of biochemical analysis in the laboratory with due regard to health and safety. Develop individual and team based biochemical analysis skills.
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is recommended before enrolment in this module.
No recommendations listed
Co-requisite Modules
No Co-requisite modules listed
Additional Requisite Information
None.
 
Indicative Content
Theory
Biomolecules and biomolecular synthesis, structure and function. Animal, plant and bacterial polysaccarides. Glycoproteins and glycolipids in membranes, energy stores and in membranes. Specialised lipids. Major enzyme groups and modes of action. Importance of cofactors including minerals and vitamins. Enzymology: reversible and irreversible inhibition. Ki. Allosteric enzymes.
Metabolism and metabolic disease:
Glycolysis and Gluconeogenesis: Review of both processes; What happens during periods of low oxygen; use of sugars other than glucose. Citric acid cycle: Review of the Citric Acid pathway; how it intersects with other metabolic pathways. Electron transport and ATP synthesis: obtaining energy from glucose. The pentose phosphate pathway and glycogen metabolism: Glucose 6-phosphate: the central component of the pentose phosphate pathway, glycogen metabolism. Regulation of carbohydrate pathways; interactions between anabolic and catabolic pathways, energy storage.
Practical
Students will build on biochemical skills developed to date and apply these in areas such as adsorption, thin-layer chromatography of lipids, enzyme analysis, enzyme assays, protein analysis and identification. Electrophoresis, crude protein extraction and chromatography.
Module Content & Assessment
Assessment Breakdown%
Continuous Assessment50.00%
Project20.00%
Practical30.00%

Assessments

Full Time

Continuous Assessment
Assessment Type Other % of Total Mark 50
Timing n/a Learning Outcomes 1,2
Non-marked No
Assessment Description
Multiple choice questions and short answer questions will be used to assess student progress in Semester 1.
Project
Assessment Type Project % of Total Mark 20
Timing n/a Learning Outcomes 1,2
Non-marked No
Assessment Description
Students will write an in-depth project on any aspect of Biochemistry in Semester 1. The topics may be chosen by the lecturer or the student.
Practical
Assessment Type Practical/Skills Evaluation % of Total Mark 30
Timing Every Week Learning Outcomes 3
Non-marked No
Assessment Description
Students will submit their Practical laboratory books after each laboratory practical for feedback.
No End of Module Formal Examination
Reassessment Requirement
Exam Board
It is at the discretion of the Examination Board as to what the qualifying criteria are.

SETU Carlow Campus reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Category Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Lecture 12 Weeks per Stage 2.00 24
Laboratory Contact Practical 12 Weeks per Stage 2.00 24
Estimated Learner Hours Non Contact Independent learning 15 Weeks per Stage 5.13 77
Total Weekly Contact Hours 4.00
 
Module Resources
Recommended Book Resources
  • Laurence A. Moran,H. Robert Horton,K. Gray Scrimgeour. (2012), Principles of Biochemistry, 5th. Prentice Hall, p.786, [ISBN: 9780321707338].
  • Nelson DL, Cox MM. (2012), Lehningers Principles of Biochemistry, 6th. Worth Publishers.
  • Jeremy M. Berg, Lubert Stryer, John Tymoczko, Gregory Gatto. (2015), Biochemistry, 9th. p.1208.
  • Donald Voet, Judith G. Voet, Charlotte W. Pratt. (2018), Voets Principles of Biochemistry, 5th. Wiley, p.1200, [ISBN: 9781119455134].
  • Biochemistry journals available in the Library.
This module does not have any article/paper resources
This module does not have any other resources
Discussion Note: